Research
  • Behavior
  • Neuroscience

Sleep contributes to preference for novel food odours in Drosophila melanogaster

Takemoto Lab · Shizuoka University — JST Global Science Campus · Shizuoka, Japan · Jul 2018 – Apr 2021

Visiting High-School Researcher · Dr. Hiroyuki Takemoto, Research Institute of Green Science and Technology

Question

Does sleep change which food odors fruit flies prefer?

What I did

  • Led a two-year independent project in high school
  • Built a sleep-deprivation rotator, a two-choice odor box and an infrared activity monitor

What I found

Sleep-deprived flies favored familiar odors over new ones. Published as a first-author paper in Scientific Reports (2021).

Methods Behavioral assays · Custom apparatus

Organism Drosophila melanogaster

Recognition Two national Grand Prizes and ministerial awards (Japan)

Background

Sleep is known to support learning and memory, and losing sleep impairs odor memory in fruit flies. Whether sleep also shapes everyday choices — like which food smell to approach — had not been tested.

What I did

As a high-school visiting researcher (JST Global Science Campus, Shizuoka University), I designed the study and built the equipment: a rotator that disturbs sleep at night, a two-choice odor box, and an infrared activity monitor.

What I found

Flies disturbed at night preferred apple cider vinegar over broth, while undisturbed flies and flies disturbed in the daytime showed a much weaker preference. Flies reared on one odor preferred that odor more strongly after sleep loss — so sleep deprivation seems to reduce interest in new odors and increase attachment to familiar ones. The work was published in Scientific Reports and presented at the Animal Behavior Society meeting.

Poster
Preview of the poster or slides

Click to open the PDF.

From this project

Fuminori Tanizawa

Fuminori Tanizawa

PhD Student

PhD Student in Computational and Systems Immunology at Stanford Medicine, studying malaria immunity

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